Villanova (33-2) scorched the nets from long range, hitting 11-of-22 3-point attempts and converting 63 percent of its field goal attempts. Lafayette (20-13) shot just 38 percent from the floor.
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Dylan Ennis scored 16 points to lead six double-figure scorers for Villanova. Dan Trist led Lafayette with a game-high 18 points.
Villanova advances to Saturday’s round of 32 in the East Region.
